Article

Distinct metabolic profiles of circulating plasmacytoid dendritic cells in systemic sclerosis patients stratified by clinical phenotypes

2024-12-02

Abstract excerpt

<h4>Background</h4> Plasmacytoid dendritic cells (pDCs) play a key role in systemic sclerosis (SSc) pathophysiology. However, despite the recognised importance of metabolic reprogramming for pDC function, their metabolic profile in SSc remains to be elucidated. Thus, our study aimed to investigate the role of pDC metabolism in SSc. <h4>Methods</h4> Peripheral blood mononuclear cells (PBMCs) were isolated from th...

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Literature Corpus work: 48070d49-ffe7-5a52-b3d9-d8bd2c3d8250
DOI: 10.1101/2024.11.27.625448

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