Article

Multimodal decoding of human liver regeneration

2023-02-25

Abstract excerpt

The liver has a unique ability to regenerate 1,2 , however in the setting of acute liver failure (ALF) this regenerative capacity is often overwhelmed and emergency liver transplantation is the only curative option 3-5 . To advance our understanding of human liver regeneration and to inform design of pro-regenerative therapies, we use paired single-nuclei RNA sequencing (snRNA-seq) combined with spatial profilin...

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Literature Corpus work: 47fb392f-2d11-5506-b8d4-d612d6536765
DOI: 10.1101/2023.02.24.529873

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