Article

Subchondral H-type Blood Vessel Formation Aggravates Articular Cartilage Degeneration through LEP-LEPR Axis

2026-01-05

Abstract excerpt

<h4>Background:</h4> Osteoarthritis (OA) is a chronic degenerative joint disease characterized by cartilage deterioration that has resulted in severe physical and economic costs for society. Risk factors for osteoarthritis encompass genetic predisposition, mechanical influences, obesity, inflammation, and metabolic problems. Recent reports indicate that the morphological alterations of subchondral bone evolve dyn...

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Literature Corpus work: 47ee5f67-5659-5ca7-8909-eb51f9630771
DOI: 10.64898/2026.01.05.697672

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