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Classification of four distinct osteoarthritis subtypes with a knee joint tissue transcriptome atlas

11 Nov 2020

Abstract excerpt

The limited molecular classifications and disease signatures of osteoarthritis (OA) impede the development of prediagnosis and targeted therapeutics for OA patients. To classify and understand the subtypes of OA, we collected three types of tissue including cartilage, subchondral bone, and synovium from multiple clinical centers and constructed an extensive transcriptome atlas of OA patients. By applying...

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PMID: 33298863
DOI: 10.1038/s41413-020-00109-x

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