Article

Discovery of shared epigenetic pathways across human phenotypes

2024-04-16

Abstract excerpt

Omics-based association studies typically consider the marginal effects of a feature, such as CpG DNA methylation, on a trait (e.g, independent models for each feature). Although some methods can assess all features together in joint and conditional estimation, this is currently done on a trait-by-trait basis. Here, we introduce MAJA, a method to learn shared and outcome-specific effects for multiple traits in mul...

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Literature Corpus work: 47bc7857-d3b5-50ed-9c22-57cd69e1093b
DOI: 10.1101/2024.04.15.589547

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