Article

In vitro evaluation of factor IX as novel treatment for factor XI deficiency

2019-04-19

Abstract excerpt

<h4>ABSTRACT</h4> Factor XI deficiency is associated with mild to moderate bleeding upon injury. Treatment of bleeding in patients can be a challenge due to the limited availability of factor XI concentrates that may also have thrombotic side effects, and the volume overload as a result of plasma transfusion. In our in vitro study, we established that recombinant factor IX concentrate Benefix® (Pfizer) was able t...

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Literature Corpus work: 47b4574e-ec3a-5662-89b0-6c4559d0d902
DOI: 10.1101/614180

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