Article
Why factor XI deficiency is a clinical concern.
Expert review of hematology - 1 Jul 2016
Wheeler Allison P, Gailani David
Abstract excerpt
INTRODUCTION: Inherited fXI deficiency has been an enigma since its discovery in 1953. The variable and relatively mild symptoms in patients with even the most severe form of the disorder seem out of step with the marked abnormalities in standard clotting assays. Indeed, the contribution of factor XI to hemostasis in an individual is not adequately assessed by techniques available in modern clinical laboratories....
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