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Recombinant Factor IX for Clinical and Research Use

1 Jul 2010

Abstract excerpt

The last significant advance in the therapy of hemophilia B was the introduction of recombinant factor IX (FIX), ensuring an advanced level of safety from potential infectious contaminants of plasma-derived clotting factors. Since that time, recombinant DNA techniques have been applied in research to elucidate the role of FIX and its functional domains within coagulation. At the same time, recombinant DNA...

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PMID: 20632248
DOI: 10.1055/s-0030-1255444

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