Article
PeakRegressor identifies composite sequence motifs responsible for STAT1 binding sites and their potential rSNPs.
PloS one - 27 Aug 2010
Pessiot Jean-François, Chiba Hirokazu, Hyakkoku Hiroto, Taniguchi Takeaki, Fujibuchi Wataru
Abstract excerpt
How to identify true transcription factor binding sites on the basis of sequence motif information (e.g., motif pattern, location, combination, etc.) is an important question in bioinformatics. We present "PeakRegressor," a system that identifies binding motifs by combining DNA-sequence data and ChIP-Seq data. PeakRegressor uses L1-norm log linear regression in order to predict peak values from binding motif...
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