Article
Key Anti-Fibrosis Associated Long Noncoding RNAs Identified in Human Hepatic Stellate Cell via Transcriptome Sequencing Analysis.
International journal of molecular sciences - 27 Feb 2018
Li Xian-Qian, Ren Zhen-Xing, Li Ke, Huang Jing-Jing, Huang Zi-Tong, Zhou Tian-Ran, Cao Hong-Ying, Zhang Feng-Xue, Tan Bo
Abstract excerpt
Hepatic fibrosis is the main pathological basis for chronic cirrhosis, and activated hepatic stellate cells (HSCs) are the primary cells involved in liver fibrosis. Our study analyzed anti-fibrosis long noncoding RNAs (lncRNAs) in activated human HSCs (hHSCs). We performed RNA sequencing (RNA-seq) and bioinformatics analysis to determine whether lncRNA expression profile changes between hHSCs activation and...
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