Article

Genome-scale functional profiling of cell cycle controls in African trypanosomes

2020-07-16

Abstract excerpt

Trypanosomatids, which include major pathogens of humans and livestock, are divergent eukaryotes for which cell cycle controls and the underlying mechanisms are not completely understood. Here, we describe a genome-wide RNA-interference library screen for cell cycle regulators in bloodstream form Trypanosoma brucei . We induced massive parallel knockdown and sorted the perturbed population into cell cycle stages...

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Literature Corpus work: 4774f183-1b26-520e-8365-95c771405727
DOI: 10.1101/2020.07.16.206698

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