Back to search

Article

Compensatory hippocampal neurogenesis in the absence of cognitive impairment following experimental hippocampectomy in adult rats

2020-06-06

Abstract excerpt

Temporal lobe epilepsy (TLE) is the commonest type of focal epilepsy in adult humans. In refractory TLE, patients are indicated for unilateral resection of the affected hippocampus (hippocampectomy), which generally does not cause any cognitive impairment. Once adult hippocampus is a region of endogenous neurogenesis, we have hypothesized that a compensatory increase in hippocampal neurogenesis might occur in the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4745d9b0-4711-5e1b-818d-7cf08d6ac8f1
DOI
10.1101/2020.06.04.135350
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Compensatory hippocampal neurogenesis in the absence of cognitive impairment following experimental hippocampectomy in adult ratsDOI 10.1101/2020.06.04.135350
Adult Hippocampal Neurogenesis and Temporal Lobe Epilepsy: A Potential Key to Understanding Cognitive DeficitSemantic proximity
Mild traumatic brain injury induces transient, sequential increases in proliferation, neuroblasts/immature neurons, and cell survival: a time course study in the male mouse dentate gyrusSemantic proximity
Increased neurogenesis in a model of electroconvulsive therapy.Semantic proximity
Experimental neonatal status epilepticus and the development of temporal lobe epilepsy with unilateral hippocampal sclerosis.Semantic proximity
Effects of single and repeated electroconvulsive stimulation on hippocampal cell proliferation and spontaneous behaviors in the rat.Semantic proximity
Repeated PTZ treatment at 25-day intervals leads to a highly efficient accumulation of doublecortin in the dorsal hippocampus of rats.Semantic proximity
Experimental neurotrophic factor therapy leads to cortical synaptic remodeling and compensates for behavioral deficits.Semantic proximity
New neurons in old brains: A cautionary tale for the analysis of neurogenesis in post-mortem tissueSemantic proximity
Increased expression of histone deacetylases 2 in temporal lobe epilepsy: A study of epileptic patients and rat modelsSemantic proximity
New neurons in old brains: implications of age in the analysis of neurogenesis in post-mortem tissueSemantic proximity
Fibroblast growth factor-2 deficiency causes defects in adult hippocampal neurogenesis, which are not rescued by exogenous fibroblast growth factor-2.Semantic proximity
Seizures, not hippocampal neuronal death, provoke neurogenesis in a mouse rapid electrical amygdala kindling model of seizures.Semantic proximity
Select a neighboring publication to make it the new centre.