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Article

Effects of single and repeated electroconvulsive stimulation on hippocampal cell proliferation and spontaneous behaviors in the rat.

Brain research - 23 Jan 2013

Nakamura Kyoko, Ito Masanobu, Liu Yinming, Seki Tatsunori, Suzuki Toshihito, Arai Heii

Abstract excerpt

Electroconvulsive therapy (ECT) has therapeutic effects on refractory depression and schizophrenia, although its biological mechanisms are still unclear. Recent studies in rodents suggest that electroconvulsive stimulation-induced seizures (ECSs) influence hippocampal adult neurogenesis, which has gained considerable traction as a possible cellular substrate for the treatment of depression. The aim of this study...

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Identifiers

PMID: 23123207
DOI: 10.1016/j.brainres.2012.10.052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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