Experimental neurotrophic factor therapy leads to cortical synaptic remodeling and compensates for behavioral deficits.

Article

Experimental neurotrophic factor therapy leads to cortical synaptic remodeling and compensates for behavioral deficits.

Journal of psychiatry & neuroscience : JPN - 1 Jan 1997

Cuello A C

Abstract excerpt

This brief review discusses experimental therapy with neurotrophic factors in a model of central nervous system (CNS) neural atrophy and synaptic loss resulting from unilateral cortical infarctions. It discusses the trophic factor protection of the cholinergic phenotype of neurons belonging to th...

Topics

Animals
Atrophy
Behavior, Animal
Cerebral Cortex
Cerebral Infarction
Nerve Growth Factors
Nerve Regeneration
Nerve Tissue Proteins
Neural Pathways
Neuronal Plasticity
Phenotype
RNA, Messenger
Rats
Synapses

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