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Article

Experimental neurotrophic factor therapy leads to cortical synaptic remodeling and compensates for behavioral deficits.

Journal of psychiatry & neuroscience : JPN - 1 Jan 1997

Cuello A C

Abstract excerpt

This brief review discusses experimental therapy with neurotrophic factors in a model of central nervous system (CNS) neural atrophy and synaptic loss resulting from unilateral cortical infarctions. It discusses the trophic factor protection of the cholinergic phenotype of neurons belonging to the forebrain-to-neocortex projection, as well as the capacity of trophic therapy to elicit synaptogenesis in the...

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Identifiers

PMID: 9002392
PMCID: PMC1188816

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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