Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Experimental neonatal status epilepticus and the development of temporal lobe epilepsy with unilateral hippocampal sclerosis.

The American journal of pathology - 1 Jan 2010

Dunleavy Mark, Shinoda Sachiko, Schindler Clara, Ewart Claire, Dolan Ross, Gobbo Oliviero L, Kerskens Christian M, Henshall David C

Abstract excerpt

Hippocampal sclerosis is a common pathological finding in patients with temporal lobe epilepsy, including children, but a causal relationship to early-life seizures remains in question. Neonatal status epilepticus in animals can result in neuronal death within the hippocampus, although macroscopic features of hippocampal shrinkage are not evident at adulthood. Here, we examined electrophysiological and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amygdala
Share to Cell Death

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Shape

Share to Electroencephalography

Share to Epilepsy, Temporal Lobe

Share to Neuropeptide Y

Share to Sclerosis

Share to Status Epilepticus

Source

Open in PubMed Open full text

Identifiers

PMID: 19948825
DOI: 10.2353/ajpath.2010.090119
PMCID: PMC2797894

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Experimental neonatal status epilepticus and the development of temporal lobe epilepsy with unilateral hippocampal sclerosis.PMID 19948825Read ↗

Molecular Genetics of Acquired Temporal Lobe Epilepsy.Semantic proximity Read ↗

Long-term hippocampal low-frequency stimulation alleviates focal seizures, memory deficits and synaptic pathology in epileptic miceSemantic proximity Read ↗

The long-term effects of febrile seizures on the hippocampal neuronal plasticity - clinical and experimental evidence.Semantic proximity Read ↗

NR1 knockdown reveals CA1 injury during a developmental period of high seizure susceptibility despite reduced seizure activity.Semantic proximity Read ↗

Hippocampal development - old and new findings.Semantic proximity Read ↗

Seizures, not hippocampal neuronal death, provoke neurogenesis in a mouse rapid electrical amygdala kindling model of seizures.Semantic proximity Read ↗

Adult Hippocampal Neurogenesis and Temporal Lobe Epilepsy: A Potential Key to Understanding Cognitive DeficitSemantic proximity Read ↗

Loss of p53 results in protracted electrographic seizures and development of an aggravated epileptic phenotype following status epilepticus.Semantic proximity Read ↗

Audiogenic kindling activates glutamatergic system in the hippocampus of rats with genetic predisposition to audiogenic seizures.Semantic proximity Read ↗

Childhood onset temporal lobe epilepsy: Beyond hippocampal sclerosis.Semantic proximity Read ↗

Neonatal seizures: gaps between the laboratory and the clinic.Semantic proximity Read ↗

Etiology matters – Genomic DNA Methylation Patterns in Three Rat Models of Acquired EpilepsySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.