Article

Targeting host sialic acids in the upper respiratory tract with a broadly-acting neuraminidase to inhibit influenza virus transmission

2023-06-03

Abstract excerpt

<h4>ABSTRACT</h4> The ongoing transmission of influenza A viruses (IAV) for the past century continues to be a burden to humans. IAV binds terminal sialic acids (SA) of sugar molecules present within the upper respiratory tract (URT) in order to successfully infect hosts. The two most common SA structures that are important for IAV infection are those with α2,3- and α2,6-linkages. While mice were once considered...

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Literature Corpus work: 4731fa52-f96a-590d-b5dc-ebc37032dc1d
DOI: 10.1101/2023.06.02.543524

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