Article
Influenza Virus Receptor Specificity and Cell Tropism in Mouse and Human Airway Epithelial Cells
13 Jul 2006
Abstract excerpt
Recent human infections caused by the highly pathogenic avian influenza virus H5N1 strains emphasize an urgent need for assessment of factors that allow viral transmission, replication, and intra-airway spread. Important determinants for virus infection are epithelial cell receptors identified as glycans terminated by an alpha2,3-linked sialic acid (SA) that preferentially bind avian strains and glycans...
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