Article

Protocol for a prospective feasibility study investigating phenoconversion of<i>CYP3A4</i>,<i>CYP2C19</i>and<i>CYP2D6</i>genotypes in paediatric and adolescent and young adult patients with an acute diagnosis of Hodgkin or Non-Hodgkin Lymphoma [PEGASUS]

2024-06-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Phenoconversion is the discrepancy between the predicted phenotype based on genotyping (genotype-based phenotype) and the actual phenotype influenced by non-genetic factors (clinical phenotype). Despite its potential impact on drug selection, efficacy, toxicity, and cancer treatment outcomes, research in this area is limited. This study aimed to assess the acceptability and...

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Literature Corpus work: 472bcb99-e18f-5089-bedb-d432ae236de5
DOI: 10.1101/2024.06.04.24308472

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Protocol for a prospective feasibility study investigating phenoconversion of<i>CYP3A4</i>,<i>CYP2C19</i>and<i>CYP2D6</i>genotypes in paediatric and adolescent and young adult patients with an acute diagnosis of Hodgkin or Non-Hodgkin Lymphoma [PEGASUS]DOI 10.1101/2024.06.04.24308472Read

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