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Article

Reaction phenotyping to assess victim drug-drug interaction risks.

Expert opinion on drug discovery - 1 Nov 2017

Di Li

Abstract excerpt

INTRODUCTION: Reaction phenotyping provides critical information regarding the fraction metabolized (fm) of drug candidates. It has become increasingly important in drug discovery and development as it can be used to assess victim drug-drug interaction potential, guide structural modification to reduce fm, inform clinical study design, predict individual variability in pharmacokinetics, and evaluate the impact of...

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PMID: 28820269
DOI: 10.1080/17460441.2017.1367280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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