Article

Histone H1 Variants Regulate Neurodevelopmental Transcriptional Programs in Autism with 16p11.2 deletion

2026-04-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Neurodevelopmental disorders, including autism spectrum disorder, involve widespread transcriptional dysregulation. Copy number variations at 16p11.2 are among the strongest genetic risk factors for autism spectrum disorder, yet the molecular mechanisms by which these copy number variations contribute to neurodevelopmental pathology remain unclear. <h4>Results</h4> We ident...

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Literature Corpus work: 47099bf7-264c-5aa3-b1a1-c107d9d88f8e
DOI: 10.64898/2026.04.15.718677

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