Article

Hypoimmunogenic Human Pluripotent Stem Cells are Valid Cell Sources for Cell Therapeutics with Normal Self-Renewal and Multi-Lineage Differentiation Capacity

2022-02-04

Abstract excerpt

<title>Abstract</title> <p>Hypoimmunogenic human pluripotent stem cells (hPSCs) are expected to serve as an unlimited cell source for generating universally compatible “off-the-shelf” cell grafts. However, whether the engineered hypoimmunogenic hPSCs still preserve their advantages of unlimited self-renewal and multilineage differentiation to yield functional tissue cells remains unclear. Here, we systematically...

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Literature Corpus work: 470456d5-a011-5f77-80f2-f169762df3fd
DOI: 10.21203/rs.3.rs-1297785/v1

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