Article

Induction of long-term allogeneic cell acceptance and formation of immune privileged tissue in immunocompetent hosts

2019-07-30

Abstract excerpt

<h4>ABSTRACT</h4> A vast number of diseases could be treated with therapeutic cells derived from pluripotent stem cells (PSCs). However, cell products that come from non-autologous sources can be immune rejected by the recipient’s immune system. Here, we show that forced expression of eight immunomodulatory transgenes, including Ccl21, Pdl1, Fasl, Serpinb9, H2-M3, Cd47, Cd200 , and Mfge8 , allows mouse embryoni...

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Literature Corpus work: cc07ae99-57fd-5785-9435-a01a8246243a
DOI: 10.1101/716571

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