Article

Translation efficiency covariation across cell types is a conserved organizing principle of mammalian transcriptomes

2024-08-11

Abstract excerpt

<h4>ABSTRACT</h4> Characterizing shared patterns of RNA expression between genes across conditions has led to the discovery of regulatory networks and novel biological functions. However, it is unclear if such coordination extends to translation. Here, we uniformly analyzed 3,819 ribosome profiling datasets from 117 human and 94 mouse tissues and cell lines. We introduce the concept of translation efficiency cov...

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Literature Corpus work: 47017e41-7f6b-57cb-9128-0fb9e2693a75
DOI: 10.1101/2024.08.11.607360

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