Article

Comparative transcriptomic analysis defines shared and mammary-specific gene expression programs across glandular tissues

2025-12-29

Abstract excerpt

<title>Abstract</title> <p>The mammary gland is an epithelial secretory organ whose development and differentiation are regulated by hormonal and transcriptional programs. While mammary differentiation has been extensively studied, how mammary gene expression relates to that of other epithelial secretory organs remains incompletely defined. Here, we performed a comparative transcriptomic analysis of human mammary...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 482f736c-79c0-5134-abb2-cfbcd0d7a68d
DOI: 10.21203/rs.3.rs-8403790/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Comparative transcriptomic analysis defines shared and mammary-specific gene expression programs across glandular tissuesDOI 10.21203/rs.3.rs-8403790/v1Read

Comparative Transcriptomics of Human Breast Tissue Suggests Conserved Epithelial Secretory Programs and Tissue-Associated Regulatory SpecializationSemantic proximity Read

Characterization of Gene Expression Signatures for the Identification of Cellular Heterogeneity in the Developing Mammary GlandSemantic proximity Read

Gene Expansion and Regulatory Rewiring Shape Sex-Biased Evolution of the Mouse Submandibular Gland SecretomeSemantic proximity Read

Mammary cell gene expression atlas links epithelial cell remodeling events to breast carcinogenesisSemantic proximity Read

Transcriptional changes in the mammary gland during lactation revealed by single cell sequencing of cells from human milkSemantic proximity Read

The Human Male Mammary Gland has Similar Epithelial Populations to Female but Distinct Composition and Transcriptional PropertiesSemantic proximity Read

Single-Cell Transcriptomes Distinguish Stem Cell State Changes and Lineage Specification Programs in Early Mammary Gland DevelopmentSemantic proximity Read

Single-cell RNA-Seq reveals cell heterogeneity and hierarchy within mouse mammary epitheliaSemantic proximity Read

FuncDECODE Resolves Cell-Type-Specific Functional Heterogeneity across Biological States and Spatial ContextsSemantic proximity Read

Transcriptome Analysis of the Normal Human Mammary Cell Commitment and Differentiation ProcessSemantic proximity Read

Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathwaysSemantic proximity Read

Deciphering the tissue specificity of the protein secretory pathway in humansSemantic proximity Read