Article

In Vitro and Ex-Vivo Direct Effects of Coagulation Factors on on Bone Cells: Exploring the Bone Remodeling Alterations in Haemophilia A

2024-08-11

Abstract excerpt

<title>Abstract</title> Haemophilia is associated with reduced bone mass and mineral density. Due to the rarity of the disease and the heterogeneity among the studies, the pathogenesis of bone loss is still under investigation. We studied the effects of coagulation factors on bone cells and characterized in a pilot study the osteoclastogenic potential of patients’ osteoclast precursors. To evaluate the effect...

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Literature Corpus work: 46aa08f6-1c55-599e-9310-8e173de5d8fc
DOI: 10.21203/rs.3.rs-4692623/v1

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