Article
Alterations in osteoclast function and phenotype induced by different inhibitors of bone resorption--implications for osteoclast quality.
BMC musculoskeletal disorders - 1 Jun 2010
Neutzsky-Wulff Anita V, Sørensen Mette G, Kocijancic Dino, Leeming Diana J, Dziegiel Morten H, Karsdal Morten A, Henriksen Kim
Abstract excerpt
BACKGROUND: Normal osteoclasts resorb bone by secretion of acid and proteases. Recent studies of patients with loss of function mutations affecting either of these processes have indicated a divergence in osteoclastic phenotypes. These difference in osteoclast phenotypes may directly or indirectl...
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