Article
Human osteoclast culture and phenotypic characterization.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012
Agrawal Ankita, Gallagher James A, Gartland Alison
Abstract excerpt
Bone remodelling occurs throughout life via the coupled actions of bone resorption and bone formation. When the balance of bone resorption and formation becomes unequal, bone diseases, such as osteoporosis occur, while the absence of functional osteoclasts leads to diseases such as osteopetrosis and pycnodysostosis. In order to develop effective treatments for bone disease the normal regulatory systems involved...
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