Article
Gene array profile identifies collagen type XV as a novel human osteoblast-secreted matrix protein.
Journal of cellular physiology - 1 Aug 2009
Lisignoli Gina, Codeluppi Katia, Todoerti Katia, Manferdini Cristina, Piacentini Anna, Zini Nicoletta, Grassi Francesco, Cattini Luca, Piva Roberta, Rizzoli Vittorio, Facchini Andrea, Giuliani Nicola, Neri Antonino
Abstract excerpt
Bone marrow stromal cells (MSCs) and osteoblasts are the two main non-haematopoietic cellular components of human bone tissue. To identify novel osteoblast-related molecules, we performed a gene expression profiling analysis comparing MSCs and osteoblasts isolated from the same donors. Genes differentially overexpressed in osteoblasts were mainly related to the negative control of cell proliferation,...
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