Article
Osteoclast markers accumulate on cells developing from human peripheral blood mononuclear precursors.
Journal of cellular biochemistry - 1 Jan 1999
Faust J, Lacey D L, Hunt P, Burgess T L, Scully S, Van G, Eli A, Qian Y, Shalhoub V
Abstract excerpt
Recent studies show that human osteoclasts develop in vitro from hematopoietic cells; however, special cultures conditions and/or cytokine mobilized peripheral blood are apparently required. Here, we report that cells expressing osteoclast markers differentiate from precursors present in nonmobilized peripheral blood mononuclear cells (PBMC), without the addition of stromal cells, growth factors, cytokines or...
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