Article
Human genetics of HCV infection phenotypes in the era of direct-acting antivirals.
Human genetics - 1 Jun 2020
Nahon Pierre, Cobat Aurélie
Abstract excerpt
The recent introduction of direct-acting antivirals (DAAs) has revolutionized hepatitis C virus (HCV) therapy by improving virus eradication rates to over 90% in most patient groups. However, the impact of DAAs on global disease burden is currently limited, and a large number of chronically infected individuals remain at risk of developing liver complications, such as liver cirrhosis and hepatocellular carcinoma...
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