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Medin Induces Pro-Inflammatory Activation of Human Brain Vascular Smooth Muscle Cells

2024-09-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Medin is one of the most common amyloidogenic proteins and accumulates in the vasculature with aging. Vascular medin accumulation is associated with Alzheimer’s disease, vascular dementia and aortic aneurysms. Medin impairs smooth muscle-dependent vasodilation in isolated human brain cerebral arteries. The role of medin in vascular smooth muscle (VSMC) activation is unknown....

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Literature Corpus work
4665f2f9-5aa5-5942-8835-7f0d1383e3ca
DOI
10.1101/2024.09.16.613366
Open publication

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Medin Induces Pro-Inflammatory Activation of Human Brain Vascular Smooth Muscle CellsDOI 10.1101/2024.09.16.613366
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