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Lactobacillus brevis Cell-Free Supernatant Recalibrates TLR-Mediated Inflammatory Signaling While Preserving Immune Competence in HT-29 Intestinal Epithelial Cells

2026-05-07

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Dysregulated Toll-like receptor (TLR) signaling in intestinal epithelial cells contributes to persistent mucosal inflammation in inflammatory bowel disease (IBD). Although <italic>Lactobacillus brevis</italic> has demonstrated anti-inflammatory potential, the pathway-level mechanisms by which its secreted metabolites influence epithelial innate immune signal...

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Literature Corpus work
4624140e-d9cb-5875-a425-e5a3e13e8e5c
DOI
10.21203/rs.3.rs-9542241/v1
Open publication

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