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Butyrate mediates anti-inflammatory effects of Faecalibacterium prausnitzii in intestinal epithelial cells through Dact3

15 Oct 2020

Abstract excerpt

The commensal bacterium Faecalibacterium prausnitzii plays a key role in inflammatory bowel disease (IBD) pathogenesis and serves as a general health biomarker in humans. However, the host molecular mechanisms that underlie its anti-inflammatory effects remain unknown. In this study we performed a transcriptomic approach on human intestinal epithelial cells (HT-29) stimulated with TNF-α and exposed to F....

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PMID: 33054518
DOI: 10.1080/19490976.2020.1826748

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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