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On Global Brain Reconfiguration after Local Manipulations

2023-09-09

Abstract excerpt

Understanding how localized brain interventions translate into whole-brain dynamics is crucial for deciphering neural function and tailoring therapeutic strategies. Combining mouse experimental datasets of focal interventions (thalamic lesion and chemogenetic silencing of cortical hubs), we demonstrate both local and global effects. Using whole-brain simulations of experimental data, we not only confirm the distri...

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Identifiers and source

Literature Corpus work
45fb694e-84ce-5930-b3c7-a297d49d6c1f
DOI
10.1101/2023.09.08.556815
Open publication

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On Global Brain Reconfiguration after Local ManipulationsDOI 10.1101/2023.09.08.556815
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