Thalamic feedback shapes brain responses evoked by cortical stimulation in mice and humans

Abstract excerpt

Cortical stimulation with single pulses is a common technique in clinical practice and research. However, we still do not understand the extent to which it engages subcortical circuits which contribute to the associated evoked potentials (EPs). Here we find that cortical stimulation generates remarkably similar EPs in humans and mice, with a late component similarly modulated by the subject’s behavioral state. We...

Topics

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• Action Potentials
• Data Interpretation, Statistical
• Databases, Factual
• Ganglia, Spinal
• Hippocampus
• Models, Neurological
• Neurons
• Phenotype

Identifiers and source

Literature Corpus work

a8a92109-322e-53c7-b101-38d7a5e3a38b

DOI

10.1101/2024.01.31.578243