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Digital Twin Brain simulation and manipulation of a functional brain network underlying mental illness

2026-03-10

Abstract excerpt

Linking synaptic-level perturbations to distributed brain-network dynamics remains a central challenge for understanding and treating mental illness. Although recent whole-brain models can reproduce individual brain activity patterns, they largely function as descriptive simulators rather than mechanistic, intervention-capable systems. Here we present an intervention-capable digital twin of the human brain, integr...

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Literature Corpus work
b77a0a34-dbc0-57f6-b71b-42ca192810af
DOI
10.64898/2026.03.06.710030
Open publication

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Digital Twin Brain simulation and manipulation of a functional brain network underlying mental illnessDOI 10.64898/2026.03.06.710030
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