Article

The role of the RNA-binding protein ZFP36L1 in suppression of replication stress-induced genomic instability

2021-01-01

Abstract excerpt

Replication stress, a hallmark of pre-cancerous and cancerous lesions, is characterised by the slowing or stalling in replication fork progression and the consequent failure to preserve genomic stability. ZFP36L1, a member of the ZFP36 family of CCCH tandem zinc finger (ZF) proteins, is an RNA-binding protein that plays a crucial role in the post-transcriptional regulation of gene expression underlying physiologic...

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Literature Corpus work: 45f79de6-073b-5e6b-a3dd-27819813a915
DOI: 10.34737/v6w00

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