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Phylodynamic estimation of the within-host mutation rate of extended-spectrum beta-lactamase-producing Enterobacterales

2025-01-31

Abstract excerpt

Despite their clinical relevance, the within-host evolution of extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-PE) is still poorly understood. To estimate the within-host mutation rates of ESBL-producing Escherichia coli and Klebsiella pneumoniae species complex, we fitted phylodynamic models to genomic sequence data of longitudinally collected rectal swabs from 64 colonized hospital patients....

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Literature Corpus work
45c2363e-0a32-5a4a-bf56-b0e6884d5ad8
DOI
10.1101/2025.01.31.635889
Open publication

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Phylodynamic estimation of the within-host mutation rate of extended-spectrum beta-lactamase-producing EnterobacteralesDOI 10.1101/2025.01.31.635889
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