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A natural history of AMR in <i>Klebsiella pneumoniae</i> : Global diversity, predictors, and predictions of evolutionary pathways

2025-09-21

Abstract excerpt

Antimicrobial resistance (AMR) is a substantial and growing global health burden. Understanding, and predicting, its evolution in specific pathogens will help responses across scales from individual patient cases to large-scale policy. Here, we use global data on AMR features, predicted from 47k Klebsiella pneumoniae genomes, with hypercubic transition path sampling to infer the evolutionary pathways by which AMR...

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Literature Corpus work
ceb2e350-49a7-5c70-b2ff-6050a0bea064
DOI
10.1101/2025.09.20.677523
Open publication

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