Article

Quantifying antibiotic impact on within-host dynamics of extended-spectrum beta-lactamase resistance in hospitalized patients

2019-02-15

Abstract excerpt

Antibiotic exposure can perturb the human gut microbiome and cause changes in the within-host abundance of the genetic determinants of drug-resistance in bacteria. Such within-host dynamics are expected to play an important role in mediating the relationship between antibiotic use and persistence of drug-resistance within a host and its prevalence within a population. Developing a quantitative representation of th...

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Literature Corpus work: 76c9507a-aaee-5fad-a74b-cc6d0ced4a0c
DOI: 10.1101/548453

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