Article
Within-host genetic diversity of extended-spectrum beta-lactamase-producing Enterobacterales in long-term colonized patients.
Nature communications - 21 Dec 2023
Aguilar-Bultet Lisandra, García-Martín Ana B, Vock Isabelle, Maurer Pekerman Laura, Stadler Rahel, Schindler Ruth, Battegay Manuel, Stadler Tanja, Gómez-Sanz Elena, Tschudin-Sutter Sarah
Abstract excerpt
Despite recognition of the immediate impact of infections caused by extended-spectrum beta-lactamase (ESBL)-producing Enterobacterales (ESBL-PE) on human health, essential aspects of their molecular epidemiology remain under-investigated. This includes knowledge on the potential of a particular strain to persist in a host, mutational events during colonization, and the genetic diversity in individual patients...
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