Article

A multi-omics integration approach relying on circulating factors does not discern endotypes in childhood type 1 diabetes.

2024-04-18

Abstract excerpt

<title>Abstract</title> <p>Type 1 Diabetes (T1D) exhibits considerable heterogeneity, impacting prediction, prevention, diagnosis, and treatment. Precision medicine aims to tailor treatments using 'endotypes'—subtypes of disease with distinct pathophysiological mechanisms. However, proposed endotypes often lack mechanistic associations with clinical outcomes, remaining elusive in T1D. This study introduces a new...

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Literature Corpus work: 45add4df-2352-502e-a327-86cc4136bb96
DOI: 10.21203/rs.3.rs-4213232/v1

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