Article
The clinical consequences of heterogeneity within and between different diabetes types.
Diabetologia - 1 Oct 2020
Redondo Maria J, Hagopian William A, Oram Richard, Steck Andrea K, Vehik Kendra, Weedon Michael, Balasubramanyam Ashok, Dabelea Dana
Abstract excerpt
Advances in molecular methods and the ability to share large population-based datasets are uncovering heterogeneity within diabetes types, and some commonalities between types. Within type 1 diabetes, endotypes have been discovered based on demographic (e.g. age at diagnosis, race/ethnicity), genetic, immunological, histopathological, metabolic and/or clinical course characteristics, with implications for disease...
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