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Development and testing of a novel Killer-Rescue self-limiting gene drive system in <i>Drosophila melanogaster</i>

2019-06-23

Abstract excerpt

We report the development and laboratory testing of a novel Killer-Rescue (K-R) self-limiting gene drive system in Drosophila melanogaster. This K-R system utilizes the well-characterized Gal4/UAS binary expression system and the Gal4 inhibitor, Gal80. Three killer (K) lines were tested; these used either an autoregulated UAS-Gal4 or UAS-Gal4 plus UAS-hid transgene. One universal rescue (R) line was used, UAS-Gal...

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Literature Corpus work
459349b0-8bc2-594b-a76a-282ca2a605a6
DOI
10.1101/680629
Open publication

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Development and testing of a novel Killer-Rescue self-limiting gene drive system in <i>Drosophila melanogaster</i>DOI 10.1101/680629
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