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Article

One prophage WO gene rescues cytoplasmic incompatibility in <i>Drosophila melanogaster</i>

23 Apr 2018

Abstract excerpt

Significance The World Health Organization recommended pilot deployment of Wolbachia -infected mosquitoes to curb viral transmission to humans. Releases of mosquitoes are underway worldwide because Wolbachia can block replication of these pathogenic viruses and deterministically spread by a drive system termed cytoplasmic incompatibility (CI). Despite extensive research, the underlying genetic basis of CI remains...

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PMID: 29686091
DOI: 10.1073/pnas.1800650115

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Related research

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Research trail→

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One prophage WO gene rescues cytoplasmic incompatibility in <i>Drosophila melanogaster</i>PMID 29686091Read ↗

One prophage WO gene rescues cytoplasmic incompatibility in <i>Drosophila melanogaster</i>Semantic proximity Read ↗

Prophage WO genes recapitulate and enhance Wolbachia-induced cytoplasmic incompatibilitySemantic proximity Read ↗

The impacts of cytoplasmic incompatibility factor (cifA and cifB) genetic variation on phenotypes.Semantic proximity Read ↗

<i>Wolbachia cifB</i> induces cytoplasmic incompatibility in the malaria mosquitoSemantic proximity Read ↗

Comparative genomics reveals factors associated with phenotypic expression of <i>Wolbachia</i>Semantic proximity Read ↗

The <i>Wolbachia</i> CinB Nuclease is Sufficient for Induction of Cytoplasmic IncompatibilitySemantic proximity Read ↗

Genomic Insights into <i>Wolbachia</i> Strain wCin2USA1 Reveal Promising Cytoplasmic Incompatibility Potential and Next-Generation Dengue BiocontrolSemantic proximity Read ↗

Evolution-guided mutagenesis of the cytoplasmic incompatibility proteins: Identifying CifA's complex functional repertoire and new essential regions in CifB.Semantic proximity Read ↗

Exploiting Wolbachia as a Tool for Mosquito-Borne Disease Control: Pursuing Efficacy, Safety, and SustainabilitySemantic proximity Read ↗

<i>Wolbachia</i> endosymbionts manipulate GSC self-renewal and differentiation to reinforce host fertilitySemantic proximity Read ↗

Symbionts and gene drive: two strategies to combat vector-borne diseaseSemantic proximity Read ↗

Temperature-sensitive cytoplasmic incompatibility across divergent <i>Wolbachia</i> partly reflects <i>cifB</i> transcription, not endosymbiont densitySemantic proximity Read ↗

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