Article
A killer-rescue system for self-limiting gene drive of anti-pathogen constructs.
Proceedings. Biological sciences - 22 Dec 2008
Gould Fred, Huang Yunxin, Legros Mathieu, Lloyd Alun L
Abstract excerpt
A number of genetic mechanisms have been suggested for driving anti-pathogen genes into natural populations. Each of these mechanisms requires complex genetic engineering, and most are theoretically expected to permanently spread throughout the target species' geographical range. In the near term, risk issues and technical limits of molecular methods could delay the development and use of these mechanisms. We...
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