Article

The role of amyloid precursor protein in neuronal and non-neuronal cell lines

2015-01-01

Abstract excerpt

Models of Alzheimer’s disease (AD) have provided useful insights into the pathogenesis and mechanistic pathways that lead to its development. One emerging idea about AD is that it may be described as a hypometabolic disorder due to the reduction of glucose uptake in AD brains. Inappropriate processing of Amyloid Precursor Protein (APP) is considered central to the initiation and progression of the disease. Althoug...

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Literature Corpus work: 454ae607-6325-5522-a044-9c1b26d37172
DOI: 10.48780/publications.aston.ac.uk.00027532

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