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Article

Glutamate, beta-amyloid precursor proteins, and calcium mediated neurofibrillary degeneration.

Journal of neural transmission. Supplementum - 1 Jan 1994

Smith-Swintosky V L, Mattson M P

Abstract excerpt

In this article we present evidence supporting the interaction between excitotoxicity, beta APP mismetabolism, metabolic compromise and intracellular calcium destabilization in the process of neurodegeneration associated with Alzheimer's disease (AD). AD is characterized by the presence of neurofibrillary tangles and amyloid-containing plaques in specific regions of the brain. There appear to be several processes...

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Source

Identifiers

PMID: 7897398
DOI: 10.1007/978-3-7091-9350-1_3

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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