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Article

Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives.

Physiological reviews - 1 Oct 1997

Mattson M P

Abstract excerpt

beta-Amyloid precursor protein (beta-APP), the source of the fibrillogenic amyloid beta-peptide (A beta) that accumulates in the brain of victims of Alzheimer's disease, is a multifunctional protein that is widely expressed in the nervous system. beta-Amyloid precursor protein is axonally transported and accumulates in presynaptic terminals and growth cones. A secreted form of beta-APP (sAPP alpha) is released...

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Source

Identifiers

PMID: 9354812
DOI: 10.1152/physrev.1997.77.4.1081

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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