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Article

Gene-modified dendritic cell vaccines for cancer.

Cytotherapy - 1 Nov 2016

Abraham Rebecca S, Mitchell Duane A

Abstract excerpt

Dendritic cell (DC) vaccines are an immunotherapeutic approach to cancer treatment that use the antigen-presentation machinery of DCs to activate an endogenous anti-tumor response. In this treatment strategy, DCs are cultured ex vivo, exposed to tumor antigens and administered to the patient. The ex vivo culturing provides a unique and powerful opportunity to modify and enhance the DCs. As such, a variety of...

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PMID: 27745604
DOI: 10.1016/j.jcyt.2016.09.009

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